Het artikel van A.Komaroff laat zien dat de pathogenese (de ontwikkeling) van ME/CFS en de ontwikkeling van 'post- covid -19 klachten' vrijwel dezelfde zijn.
Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of post-acute COVID-19 syndrome
Komaroff AL, Lipkin WI. Trends in Molecular Medicine. 2021 Jun 7:S1471-4914(21)00134-9. [Online ahead of print]
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause chronic and acute disease. Post-acute sequelae of SARS-CoV-2 infection (PASC) include injury to the lungs, heart, kidneys, and brain that may produce a variety of symptoms. PASC also includes a post-coronavirus disease 2019 (COVID-19) syndrome (‘long COVID’) with features that can follow other acute infectious diseases and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Here we summarize what is known about the pathogenesis of ME/CFS and of ‘acute’ COVID-19, and we speculate that the pathogenesis of post-COVID-19 syndrome in some people may be similar to that of ME/CFS. We propose molecular mechanisms that might explain the fatigue and related symptoms in both illnesses, and we suggest a research agenda for both ME/CFS and post-COVID-19 syndrome.
Publicatie: 04/07/2021Terug naar nieuwsoverzicht